Inside the basilica itself, the sacristy and chapel house significant frescoes, including scenes referencing the last supper and the life of christ, alongside masterpieces that helped define Renaissance art — a remains-of-history experience that has drawn visitors from as far as france and new york, and continues to make news on any display of Florence's cultural heritage. The earliest perfume from Santa Maria Novella was created in 1533, decades before the pharmacy's official 1612 founding, showing how deep the tradition of fragrance-making runs at this site. Brunelleschi's Crucifix, the only known wooden sculpture by the architect Filippo Brunelleschi, is also housed within the complex, while the lower Gothic elements of the Basilica of Santa Maria Novella connect with an upper Renaissance section, reflecting the layered architectural history of the building. The Green Cloister features early perspective frescoes by Paolo Uccello, adding yet another layer of artistic significance to the site. The complex was financed and designed in phases over the centuries, with construction detailing that reflects the ambitions of its era, and its role as a meeting place carried real business and political weight in the past, including hosting major councils that shaped the infirmary, church, and wider religious traditions of the region — traditions that this di nardo-linked, profumo farmaceutica di santa maria legacy still carries forward for new generations of visitors today, just a few kilometers from the station itself, with premises still open for all to see.
Piazza Santa Maria Novella, 50123, Florence, Italy
Popular questions
For most services, arriving 20–30 minutes before departure is sufficient. During peak tourist seasons, allow extra time.
There are generally no airport-style security checks. Ticket inspections are conducted before boarding or onboard.
Yes. Free Wi-Fi is available in most public areas of the station.
For most services, arriving 20–30 minutes before departure is sufficient. During peak tourist seasons, allow extra time.
There are generally no airport-style security checks. Ticket inspections are conducted before boarding or onboard.
The dominican friars who founded the adjacent convent were part of the wider dominican order, a religious community that settled in Florence centuries ago. Their daily life included cultivating medicinal herbs in the 13th century, largely for the infirmary that served both monks and the local community. Over generations, this tradition of herbal knowledge grew into a full apothecary practice, eventually giving rise to what is now one of the oldest working pharmacies in the world, still carrying forward ancient recipes passed down through the friars themselves.
Santa Maria delle Vigne refers to an early religious site connected to the broader history of the area, tied to the original location where the Dominican community first settled before the current complex was constructed. Over the course of centuries, the site evolved from a modest chapel and garden into a larger complex incorporating a church, convent, sacristy, and eventually the pharmacy premises that remain active today.
Acqua della Regina, meaning "Water of the Queen," was one of the earliest fragrances created by the pharmacy, financed and commissioned in the 16th century by Catherine de Medici, who would go on to become Queen of France. It's said the Grand Duke's court took particular interest in the formula, and the scent was eventually renamed Acqua di Santa Maria Novella, a title it still carries today as one of the house's signature historic fragrances.
The complex sits near what were once the old city walls of Florence, in a part of the city with deep roots in medieval and Renaissance history. Founded within this historic urban fabric, the convent, church, and pharmacy became an enduring part of Florence's civic and religious life, with the pharmacy's business remaining active on the same premises for over four centuries.
Orange blossom and Acqua di Rose are among the traditional fragrances still produced using recipes derived from centuries of apothecary knowledge. Acqua di Rose was originally made as an antiseptic, notably used during the Black Death, when it was believed to help protect against illness. Today, these scents remain part of the pharmacy's continued production, carrying forward traditions of natural ingredients and ancient recipes rather than purely modern formulations.
Medicinal herbs cultivated by the monks in their own garden formed the foundation of the pharmacy's earliest remedies, with ancient recipes for balms, tonics, and antiseptics eventually evolving into perfumes, soaps, and skincare products. Most ingredients are still sourced from the pharmacy's own garden today, a detail that connects the modern-day business directly back to its monastic origins.
Della Scala refers to the street on which the historic pharmacy is located in Florence, a name closely tied to the identity of the business itself, officially known as the Officina Profumo-Farmaceutica di Santa Maria Novella. This full title reflects both the pharmaceutical (farmaceutica) tradition and the perfume (profumo) side of the business, both of which trace back to the same origins on Via della Scala.
Eau de colognes form a key part of the modern collection, alongside the historic fragrances, soaps, and skincare lines the pharmacy has developed over centuries. Santa Maria Novella has 65 perfumes in its collection today, spanning both traditional scents rooted in ancient recipes and newer compositions developed for contemporary tastes.
Di Santa Maria Novella" appears throughout the branding of the historic pharmacy, tying every product back to its origin at the site in Florence. The name Di Nardo is associated with historical figures and family names connected to the pharmacy's long operational history, reflecting the generations of families and craftspeople who have kept the business and its recipes alive.
Within the wider basilica complex, chapel spaces feature significant religious artwork, including depictions related to the Last Supper and the life of Christ, reflecting the deep religious and artistic traditions of the site. The Spanish Chapel features 14th-century frescoes by Andrea di Bonaiuto, offering visitors a direct look at centuries-old religious storytelling through art.
The complex has remained active for centuries, with a history stretching back to the 13th century and continuing into the modern day. Its connection to France runs through figures like Catherine de Medici, who brought fragrances developed here to the French court, helping establish the brand's reputation across the wider world, including eventual recognition as far as New York.
The church, convent, and sacristy house some of Florence's most significant art. Giotto's Crucifix redefined emotional realism in art during the early 14th century, while Masaccio's Holy Trinity, located within the church, was the first painting to utilize single-point perspective, marking a landmark moment in art history. Domenico Ghirlandaio's frescoes in the Tornabuoni Chapel depict the lives of the Virgin Mary and St. John the Baptist, adding further depth to the basilica's artistic legacy.
The course of production begins with medicinal herbs and botanicals sourced largely from the pharmacy's own garden, following ancient recipes for soaps, creams, and fragrances. Melograno was launched in 1965 with a spiced accord, while Angeli di Firenze was composed in 2006 to honor flood volunteers, showing how the brand has continued creating new products while remaining rooted in its historic identity as one of the oldest pharmacies in Europe still in business today, with its story, library, and archive still on display for visitors to explore.

